When excess sugar enters the bloodstream, it binds to proteins like collagen and elastin. This chemical reaction creates cross-linked proteins known as Advanced Glycation End-products (AGEs).
Healthy collagen is springy and resilient, but glycation makes it brittle and weak. This leads to premature skin sagging, deep creases, and a loss of healthy, youthful bounce.
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Board-Certified Dermatologist & Biomedical Researcher
Dr. Vivienne Chen is a board-certified dermatologist and biomedical researcher with over 12 years of clinical experience in cellular aging, peptide therapies, and skin barrier health.
It is difficult to reverse, but you can prevent it by limiting refined sugars, consuming antioxidant-rich foods, and using anti-glycation topicals containing carnosine.
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